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Chemical & Engineering News Nov 22, 2004 pg 83

Metabolic Syndrome from article by A.Maureen Rouhi

Metabolic syndrome can affect anyone of any weight.  Increases risk of heart disease. Diagnosis is based on accumulation of fat around the waist, blood pressure, levels of key lipids, and glucose levels.  Eating right and exercise are first line of defense.   Cost in 2003 was 6 million hospitalizations and 1 million deaths costing $350 billion.  It is estimated the 47 million US adults have it. 16% of kids are overweight.  Genetics is a factor.  It can be caused by a single mutation in mitochondrial DNA. Risk rises from 25% at 35 yrs old to 40% at 60.  18% of men and 22% of women of near normal weight have the syndrome.  Insulin resistance is central in the syndrome.  Glucose increases in the bloodstream, increasing advanced glycation end products (AGE).  These trap LDL particles in arterial walls, and are linked to cataracts and poor kidney function.

Do you have it?  Probably if you have 3 of these 5 parameters:

1. Waist circumference greater or equal to 40 inches in men, 35 in women

2. Triglycerides above 150 mg/dL

3. HDL less than or equal to 40mg/dL men; 50mg/dL women

4. Blood pressure greater than or equal to 130/85 mm Hg

5. Fasting glucose greater than or equal to 110 mg/dL

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