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SUBJ: Sept Nutrition notes from Roc, Nutrition investigator
Scientific experiments are often not reproducible because subjects have different microbiomes. This is a tremendous realization of why even with “identical mice,” results are often completely different. Drug and nutrition experiments among “identical subjects” are confusing because every subject has a different microbiome. Science 353: 741 (19 Aug 2016)
20mg of CURCUMIN daily prevents muscle damage by regulating NF kB and Nrf2 pathways and improves performance an in vivo model
Staying active makes physical age much less than chronological age. In clinical settings, there is an occasional mismatch between chronological age and physical age. We evaluated whether activities of daily living (ADL), which reflect physical age, also predict complications and prognosis in elderly patients with AMI; People age 50 to 80 who exercise 40 min/day 3 times per week for 6 months had larger hippocampi, controls had smaller ones. Exercise reduced Alzheimer’s risk 50% in those over age 65. AARP Bulletin, Sept, 2016, pg 26.
Cognitively impaired trauma patients proved to be especially at risk of malnutrition. Since 96 hours of parenteral nutrition as a crisis intervention was insufficient, additional supplementation could be considered.
AGEISM: the level of development of a country and the lack of government spending on older people (pension and health care systems) may contribute to their younger counterparts perceiving them more negatively.
Medicare costs could be reduced by prevention of future fractures if osteoporosis were treated. PLASMA homocysteine level is a risk factor for osteoporotic fractures in elderly patients
Reader’s question: Are there benefits of MCT [medium chain triglycerides] oil? They may improve Alzheimer’s symptoms! From a 2014 publication (pay to see it all)(free abstract), it is possible. “Medium-chain triglycerides (MCTs) are metabolized to ketone bodies that serve as an alternative source of energy for neurons. Data from clinical trials suggest that MCTs improve cognition in patients with mild to moderate AD in apolipoprotein E4-negative patients. Adverse events observed were mild and included minor gastrointestinal problems such as diarrhea, dyspepsia, and flatulence.”
Reader’s question: Got advice on rheumatoid arthritis? Please see my nutrition web page for many useful links.
- Roc, Nutrition Investigator