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SUBJECT: Notes for Jan from Roc Nutrition Investigator
Burnout - Here’s a path to help you. NIH Pathways to Prevention Workshop: Total Worker Health®—What's Work Got to Do With It? Download the Panel's Draft Report (PDF - 114 KB). The report summarizes the workshop and identifies future research priorities. Physician burnout is skyrocketing - 52% of doctors report feeling burned out during the past year.
For younger people:
For mature people:
Inflamm-aging is a major factor shortening healthspan - Miriam Capri (University of Bologna) addressed the agerelated problem of “inflamm-aging,” which is characterized by sustained low-level inflammation, chronic activation of certain immune cells called macrophages, oxidative damage, and a physiological blurring of “self” and “non-self.” The gut microbiome declines in diversity with age and, in
Senescent cells have stopped dividing, but they continue to be metabolically active and secrete pro-inflammatory molecules that help in wound healing and injury repair but are otherwise damaging. Smoking, excessive alcohol intake, high-fat diets, and other factors induce cellular senescence. Vitamin E and other antioxidants, as well as exercise, may be protective.
Vitamin D, lipoic acid, a Mediterranean diet that emphasizes polyunsaturated fats and flavonoids, exercise, an enriched environment, and mental training, as well as caloric restriction, dietary polyphenols, and polyunsaturated fats, helps old brains. Studies have shown that these factors can improve cognitive and motor functions like balance and gait instability in older age. Although the number of neurons doesn’t decline much with age, they shrink and the number of synapses decreases. Exercise increases neurogenesis and brain volume, an enriched environment increases neurogenesis, vitamin D increases certain brain receptors, lipoic acid improves longterm memory, and a Mediterranean diet that emphasizes polyunsaturated fats and flavonoids helps old brains.
This study show how important social interactions are to delaying frailty in people over 65. It demonstrates the close relationship between frailty and psychosocial factors, suggesting the need to take into account simultaneously physical and psychosocial components of human functioning.
We found evidence of altered circadian rhythms with a reduced nocturnal melatonin response at 4 am in men with cognitive impairment. Getting enough sleep and using melatonin may be helpful to delay cognitive decline.
There is preliminary evidence showing the potential benefit of momentum-based dumbbell training for improving cognitive function in older adults with MCI.
Since 1965, life expectancy for people age 65 has increased 15 years. Someone now 60-65 can expect to live to 85-90!
- Roc, Nutrition Investigator