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SUBJECT: AJCN Feb 2013
1.CoQ10 supplements may not be safe or effective - CoQ10 is synthesized in tissues, and under normal physiologic conditions, the bioavailability of dietary CoQ10 is very low for most tissues including the heart. In situations of severe CoQ10 deficiency such as genetic CoQ10 deficiency, however, dietary supplements alleviate pathologic conditions and restore mitochondrial and other functions. It is important to remember that improvements in LVEF and NYHA class after a short follow-up period do not establish that the therapeutic intervention is safe or effective during long-term administration.
2. Leucine and BCAA supplements stimulate muscle repair but also activate the mTORC pathway that may accelerate aging - In skeletal muscle, oral administration of either leucine alone or a protein-containing meal leads to a stimulation of the rate of protein synthesis concomitant with activation of mTORC1.
3. Multivitamins have no effect on mortality in elderly - Should meta-analyses trump observational studies? Authors conducted a meta-analysis of multivitamin-multimineral (MVMM) supplementation trials to determine the effect on mortality when used for primary or secondary prevention. The authors did not find support for increased safety risks when independently living adults use MVMM supplements. They found, in fact, that MVMM supplementation had no effect on mortality in either direction.
4. Fruit vs snack video games have no effect on which of them kids eat - Children who played the fruit version of the advergame did not eat significantly more fruit than did those in the other groups.
5. Fish oil reduces inflammation - Three short perioperative infusions of n−3 PUFAs reduce systemic inflammation induced by cardiopulmonary bypass surgery: a randomized controlled trial. Perioperative FO infusions significantly increased PUFA concentrations in platelet and atrial tissue membranes within 12 h of the first FO administration and decreased biological and clinical signs of inflammation. These results suggest that perioperative FO may be beneficial in elective surgery.
6. No difference in effect of low fat vs. low carb diet - We showed no evidence that an LGD and an LFD differ in efficacy for the reduction of BMI or aspects of metabolic syndrome in obese Hispanic youth.
7. Vitamin B12 and folate predict mental development in malnourished children 12-18 mos old- Cobalamin and folate status showed a statistically significant association with cognitive performance.
9. Dietary fiber, esp. from veggies, reduce breast cancer risk 5% - Not much effect, but one more reason to avoid meat.
10. More time nursing babies reduces risk of ovarian cancer - One more reward for breast feeding. Significant inverse dose-response relations were found for both duration of lactation and the number of children breastfed. The adjusted ORs were 0.09 for women with ≥31 mo of total lactation and those with ≤10 mo of lactation and 0.38 for women with ≥3 children breastfed compared with those with one child breastfed.
12. Educational level is the strongest indicator of cognitive reserve.This study did not find support for a beneficial effect of MedDiet adherence on cognitive function, irrespective of educational level, which is the strongest indicator of cognitive reserve.
13. High saturated fat intake reduces sperm count in young men. Our findings are of potentially great public interest, because changes in diet over the past decades may be part of the explanation for the recently reported high frequency of subnormal human sperm counts. A reduction in saturated fat intake may be beneficial for both general and reproductive health.
14. Poor diet is a risk factor for depression - Poor diet increases the risk by 41% in women, and good diet reduces the risk of recurrence of depression by 65%.
- Roc, Nutrition Investigator