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J Nutrition June 2005

Eun-Soo Han and Morgen Hickey

Microarray Evaluation of Dietary Restriction

 J. Nutr. 2005 135: 1343-1346.

A comparison of altered genes by DR in mice, rats, pigs, monkeys, yeast, and flies showed no common gene altered by DR among different species. It seems that individual genes altered in the expression by DR were constrained within species.

Chung-Yen Chen, Paul E. Milbury, Karen Lapsley, and Jeffrey B. Blumberg

Flavonoids from Almond Skins Are Bioavailable and Act Synergistically with Vitamins C and E to Enhance Hamster and Human LDL Resistance to Oxidation

 J. Nutr. 2005 135: 1366-1373

Consumption of tree nuts such as almonds has been associatedwith a reduced risk of coronary heart disease. Flavonoids, foundpredominantly in the skin of almonds, may contribute to theirputative health benefit,… they are bioavailable and actin synergy with vitamins C and E to protect LDL against oxidation…

Richard T. Tulley et al

Daily Intake of Multivitamins during Long-Term Intake of Olestra in Men Prevents Declines in Serum Vitamins A and E but Not Carotenoids

 J. Nutr. 2005 135: 1456-1461

We concludethat supplementation with a multivitamin containing vitaminsA and E was adequate to prevent olestra-induced decrease inserum -tocopherol and retinol. Olestra-induced decreases inserum ß-carotene, lycopene, and lutein + zeaxanthinwere not prevented by the vitamin supplement used in this study.

Julio Villena et al

Lactobacillus casei Improves Resistance to Pneumococcal Respiratory Infection in Malnourished Mice

 J. Nutr. 2005 135: 1462-1469

This study suggests thatthe addition of L. casei to the repletion diet has a beneficialeffect because it accelerates the recovery of the innate immuneresponse and improves the specific immune mechanisms againstan S. pneumoniae respiratory infection in malnourished mice.

[Lactobacillus casei are present in the intestine, and are reported to induce both a secretory immune response and to protect against enteric infections in well-nourished and mal-nourished animals.]


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