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The Nutrition InvestigatorThe health and nutrition blog by Dr. Roc Ordman.


by Roc (click here for full post)

Sorry this is not better organized. But I figure if you have fibromyalgia, it is worth reading and discussing with your physician.  (One person who did had their doctor recommend medical marijuana for pain!)

PRIMARY RESULT: Consider trying hyperbaric oxygen for pain relief.

Hyperbaric oxygen gives 100% pain relief – half of the 48 patients who completed it received 40 HBOT treatments five days a week over two months. The 90-minute treatments exposed patients to pure oxygen at two times the atmospheric pressure.

 2017 report it works: The study provides evidence that HBOT can improve the symptoms and life quality of FMS patients. Moreover, it shows that HBOT can induce neuroplasticity and significantly rectify abnormal brain activity in pain related areas of FMS patients.

PROTOCOL: The HBOT protocol comprised 40 sessions, 5 days/week, 90 minutes, 100% oxygen at 2ATA. Administered in cylindrical chambers, the therapy has been approved by the U.S. Food and Drug Administration to treat 14 conditions, including decompression sickness among scuba divers, diabetic wounds, radiation injury from cancer treatments, serious infections, severe burns, and carbon monoxide poisoning. Fibromyalgia is not one of the currently FDA-approved conditions for hyperbaric oxygen therapy, which continues to be tested for this and other “off-label” conditions.

But health insurance or Medicare are unlikely to cover the cost of hyperbaric oxygen therapy for fibromyalgia at this point, since it’s not one of the FDA-approved uses. According to the Duke Center for Hyperbaric Medicine and Environmental Physiology in North Carolina, the total cost of the 30 to 60 treatments required for most conditions can approximate that of a major surgical procedure — tens of thousands of dollars.

Does hyperbaric treatment last? The researchers did find some discrepancies among patients with different fibromyalgia catalysts. When fibromyalgia was triggered by a traumatic brain injury, for example, they witnessed a complete resolution without any need for further treatment. But when the trigger was attributed to other causes, such as fever-related diseases, patients required periodic maintenance therapy.

Clinical trial of hyperbaric – https://clinicaltrials.gov/ct2/show/NCT03325959.  60 daily hyperbaric oxygen treatment sessions will be administrated 5 days per week. Each session will include exposure of 90 minutes to 100% at 2 ATA, with 5 minutes air breaks every 20 minutes. (starting Oct 30, 2017)


Simple Business Financing for Offices or Clinics
If you are looking for a hyperbaric chamber for your place of business, Direct Capital offers several financing options for you.  The current terms include no money down with a first payment of $49 due within 30 days followed by five additional payments of $49 due monthly. The out of pocket costs total $294 in the first 6 months.

SUMMARY OF OTHER FINDINGS (see Results below for details/sources):

  1. Take 50,000 IU Vitamin D every other week (or 2,000 IU per day)
  2. Take ribose (5 grams three times a day)
  3. niacin 2g/day
  4. yoga
  5. Low-dose naltrexone(LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome.
  6. L-theanine 100-200mg/day or black tea 4-8 cups/day
  7. Mindfulness meditation – there are CDs and online tapes for this.
  8. SAMe 400 mg BID
  9. Hyperbaric oxygen gives 100% pain relief – half of the 48 patients who completed it received 40 HBOT treatments five days a week over two months. The 90-minute treatments exposed patients to pure oxygen at two times the atmospheric pressure.


  1. Pain therapy has 100% success.Israeli and US trials of Israeli-developed Hyperbaric (high-pressure) Oxygen Therapy (HBOT) reported relief for all 48 sufferers of the chronic pain condition fibromyalgia.  Dr. Shai Efrati, lead author of the study at the Assaf Harofeh Medical Center noted his own mother suffers from the syndrome.

(See previous newsletters here)  http://news.rice.edu/2015/06/02/hyperbaric-hope-for-fibromyalgia-sufferers-2/

  1. Control disease – deactivate genes.Scientists at Israel’s Technion have discovered how to use proteins to suppress unwanted gene activity. It could lead to a cure for cystic fibrosis and sickle-cell anemia, as well as more common diseases that are caused by gene activity or mutations, such as many forms of cancer.


  1. Do not know where I found this for my website: http://www.nutritioninvestigator.org/Nutrition/aillum/SAMe.htm
  2. Mindfulness-based therapy is wonderful medicine – for headaches, insomnia, fibromyalgia, depression, irritable bowel syndrome, stress (which interferes with getting pregnant).
    ….Meditation often makes drugs more effective, and frequently meditation can replace medications and be more effective than the drugs are.
    Once anxious patients are identified, mindful meditation tames worrying by directing mental focus to the present moment. People treated for cancer and given an 8 week meditation class stayed relaxed for at least a full year, while those without the course were often anxious about their health.
    5.    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/

2. https://www.ncbi.nlm.nih.gov/pubmed/17109576

DESIGN:Forty-one (41) patients with a diagnosis of FMS and/or CFS were given D-ribose, a naturally occurring pentose carbohydrate, at a dose of 5 g t.i.d. for a total of 280 g. All patients completed questionnaires containing discrete visual analog scales and a global assessment pre- and post-D-ribose administration.


D-ribose, which was well-tolerated, resulted in a significant improvement in all five visual analog scale (VAS) categories: energy; sleep; mental clarity; pain intensity; and well-being, as well as an improvement in patients’ global assessment. Approximately 66% of patients experienced significant improvement while on D-ribose, with an average increase in energy on the VAS of 45% and an average improvement in overall well-being of 30% (p < 0.0001).


D-ribose significantly reduced clinical symptoms in patients suffering from fibromyalgia and chronic fatigue syndrome.
Below are two comments documented at this site related to fibromyalgia. Take at least 1,000 IU per day, in July, 2008 I have read 2,000 IU daily is worthwhile and safe. Also, the note 2 below indicates that ribose and theanine may be of use.
1. Vitamin D: More than bone health, based on remarks by Dr. Michael F. Hollick, Prof of Medicine, Physiology and Biophysics at Boston Univ. School of Medicine, Director of Osteoporosis Center at BU. ” The Importance of Vitamin D in prevention of osteoporosis and other chronic diseases,” presented at the Linus Pauling Institute “Diet and Optimal Health” conference, Portland, OR, May 20, 2005 – But he stated 40-60% of fibromyalgia is actually lack of vitamin D and misdiagnosed by medical experts. People would benefit most from a dosage of 50,000 IU taken every other week; a dose of 1,000 iu per day also works [http://www.beloit.edu/~nutritio/vitD.htm]

2 and 6. L-theanine and ribose: Dear Doc Roc,
Newest issue of “Alternative” has an article on fibromyalgia in which one researcher gave subjects “5 grams of ribose three times a day, for an average of 28 days” leading to “significant improvement in energy, sleep, mental clarity, and pain intensity with a 44 percent average increase in energy and an overall 30 percent increase in well-being.” Same researcher also advises 200 mg of “L-theanine (it must be the ‘L’ form)” to promote sleep, one of any fibromyalgia patient’s biggest issues.. Any problem with either? Are they obtainable for non-research purposes? Thanks. Have a great week. Mary
Dear Mary Carol, Research/Nutrition literature is exploding with things showing promise, though I do not have time to explore them thoroughly. As neither topic was in my favorite nutrition journals, I do not trust either yet. But both ribose and theanine are safe. The L- just means the particular form stereochemically, so I don’t bother to type it. Note in both cases the articles are very recent. Officially I cannot say anything, but personally, they look quite promising. Meanwhile, MDR has a product called Fibromy Support.
1. Pharmacotherapy. 2004 Nov;24(11):1646-8. Benefit of ribose in a patient with fibromyalgia. Gebhart B, Jorgenson JA. Ribose was added to the existing treatment regimen of a woman with fibromyalgia, resulting in a decrease in symptoms. It has been postulated that patients with fibromyalgia may have an alteration in muscle adenine nucleotide metabolism, leading to depleted energy reserves… As a key component in adenine nucleotide synthesis, ribose supplementation may be useful in such patients.
2. Biol Psychol. 2006 Aug 21; l-Theanine reduces psychological and physiological stress responses. Kimura K, Ozeki M, Juneja LR, Ohira H. l -Theanine is an amino acid contained in green tea leaves which is known to block the binding of l-glutamic acid to glutamate receptors in the brain. Because the characteristics of l-Theanine suggest that it may influence psychological and physiological states under stress, the present study examined these possible effects in a laboratory setting using a mental arithmetic task as an acute stressor. Twelve participants underwent four separate trials: one in which they took l-Theanine at the start of an experimental procedure, one in which they took l-Theanine midway, and two control trials in which they either took a placebo or nothing. The experimental sessions were performed by double-blind, and the order of them was counterbalanced. The results showed that l-Theanine intake resulted in a reduction in the heart rate (HR) and salivary immunoglobulin A (s-IgA) responses to an acute stress task relative to the placebo control condition…Thus, it was suggested that the oral intake of l-Theanine could cause anti-stress effects via the inhibition of cortical neuron excitation.



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